Author

Priscilla Rubio

Trinity CollegeORCID 0009-0006-7264-2418Unclaimed ORCID profile · follow to get notified of new preprints

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Approach:experimental assay· 1

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Jonathan AshbyiD· 1 shared Michael C. PuljungiD· 1 shared Sharon WhitakeriD· 1 shared

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1 shared paperBiophysics

Jonathan AshbyORCID

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1 paper

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BiophysicsThe Journal of General PhysiologyPeer-reviewedAug 21, 2026

A fluorescent non-hydrolyzable probe for the nucleotide binding sites of KATP

Priscilla Rubio, Sharon Whitaker, Jonathan Ashby, Michael C. Puljung

This paper develops a fluorescent ATP analog to study nucleotide binding sites on KATP channels, showing that non-hydrolyzable ATP analogs can bind to SUR1 sites and do not fail to activate KATP due to binding issues.

DOI 10.1085/jgp.202513840

experimental assay

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