This study identifies genetic variants associated with REM sleep behavior disorder in Parkinson's disease and explores genetic correlations with neuropsychiatric traits.

npj Parkinson s Disease · Sep 25, 2025Peer-reviewedGenetic & Genomic Medicine

Analysis of PTRHD1 common and rare variants in European patients with Parkinson's disease

Yuri Ludwig Sosero, Sara Bandrés‐Ciga, Ziv Gan‐Or, Lynne Krohn

The paper investigates whether variants in the PTRHD1 gene are associated with Parkinson's disease risk and age at onset in European populations, finding no significant associations.

Neurobiology of Aging · Nov 1, 2021Peer-reviewedGenetic & Genomic Medicine

Fine mapping of the HLA locus in Parkinson's disease in Europeans

Eric Yu, Aditya Ambati, Maren Stolp Andersen, Lynne Krohn, Mehrdad A. Estiar, Prabhjyot Saini, Konstantin A. Senkevich, Yuri Ludwig Sosero, Ashwin Ashok Kumar Sreelatha, Jennifer A. Ruskey, Farnaz Asayesh, Dan Spiegelman, Mathias Toft, Marte Kathrine Viken, Manu Sharma, , Ziv Gan‐Or

This study fine maps the association between HLA genes and Parkinson's disease in Europeans, identifying specific amino acid variants in HLA-DRB1 that are protective against PD.

npj Parkinson s Disease · Sep 21, 2021Peer-reviewedGenetic & Genomic Medicine

Lack of evidence for genetic association of saposins A, B, C and D with Parkinson disease

Yuri Ludwig Sosero, Sara Bandrés‐Ciga, Sharon Hassin‐Baer, Roy N. Alcalay, Ziv Gan‐Or

The paper examines genetic associations of saposins A, B, C, and D with Parkinson's disease using SKAT-O and GWAS analyses, finding no significant associations.

medRxiv · May 31, 2020 · PreprintGenetic & Genomic Medicine