Evolutionarily Conserved Plasmodium falciparum HSP70-3 Enhances the Immunogenicity of the Established Malaria Vaccine Antigen Circumsporozoite Protein through Cross-Presentation
Prachi Garg, Chandan Kumar Verma, Kanika Gupta, Ayushee Sharma, Shivam Jawla, Neha Jha, Savita Saini, Kota Arun Kumar, Anand Ranganathan, Shailja Singh
This paper shows that PfHSP70-3-SBD enhances PfCSP immunogenicity through cross-presentation, improving vaccine efficacy against malaria.
bioRxiv · Oct 16, 2026 · PreprintMicrobiology