Beware the Jaccard: the choice of metric is important and non-trivial in genomic colocalisation analysis.
Stefania Salvatore, Knut Dagestad Rand, Ivar Grytten, Egil Ferkingstad, Diana Domańska, Lars Holden, Marius Gheorghe, Anthony Mathelier, Ingrid K. Glad, Geir Kjetil Sandve
The paper shows that the choice of metric significantly affects genomic co-occurrence analysis and proposes alternative approaches to guide this choice.
Briefings in Bioinformatics · Jun 18, 2019Peer-reviewedBioinformatics