Author

Jaison Jain

Brown UniversityORCID 0000-0002-9478-5018Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Research Focus:batch correction / integration· 1 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Assay:CITE-seq· 1

Frequent Co-Authors

Andrew ButleriD· 2 shared Rahul SatijaiD· 2 shared Tim StuartiD· 2 shared Aaron J. WilkiD· 1 shared Alexia BrowniD· 1 shared Alsu M. MissarovaiD· 1 shared Angela J. RogersiD· 1 shared Avi SrivastavaiD· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioinformatics

Andrew ButlerORCID

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3 papers

Recent·Most cited

BioinformaticsGenome biologyPeer-reviewedDec 1, 2021

geneBasis: an iterative approach for unsupervised selection of targeted gene panels from scRNA-seq.

Alsu M. Missarova, Jaison Jain, Andrew Butler…·John C. Marioni

geneBasis selects an optimal gene panel from scRNA-seq data by iteratively adding genes that maximize manifold distance, outperforming existing methods in resolving cell types and states.

49 citations

scRNA-seqstatistical model

𝕏 PostBluesky

GenomicsbioRxivPreprintOct 28, 2021

Sciara coprophila larvae upregulate DNA repair pathways and downregulate developmental regulators in response to ionizing radiation

John M. Urban, Jack R Bateman, Kodie Garza…·Susan A. Gerbi

This study identifies DNA repair pathway upregulation and developmental regulator downregulation in Sciara coprophila larvae exposed to ionizing radiation.

DOI 10.1101/2021.10.28.466123

bulk RNA-seqstatistical model

𝕏 PostBluesky

GenomicsCellPeer-reviewedMay 31, 2021

✦ In-depth digest

Integrated analysis of multimodal single-cell data

Yuhan Hao, Stephanie Hao, Erica Andersen‐Nissen…·Rahul Satija

Weighted-nearest neighbor (WNN) analysis in Seurat v4 learns per-cell modality weights to define cell states, enabling a 228-antibody human PBMC CITE-seq reference for RNA-only query mapping.

15,523 citationstop 1%

humanmouse

𝕏 PostBluesky