Aaron J. Wilk

CellVoyager autonomously analyzes scRNA-seq data to generate new hypotheses and findings, outperforming existing models and producing scientifically interesting results.

The paper shows that NK cell activation during SARS-CoV-2 infection correlates with reduced neutralization breadth of antibodies.

The paper presents a multimodal epigenome atlas of human immune cells exposed to viral and chemical agents, revealing epigenetic changes in transcription factor binding sites and cytokine networks.

This paper identifies activated interstitial macrophages as a key target of SARS-CoV-2 infection in human lung tissue, showing their role in viral takeover, inflammation, and fibrosis.

The paper uses CRISPRa screening and real-world data to identify KCNA6 as a neuronal entry factor for SARS-CoV-2 and shows dalfampridine can suppress viral entry.

Weighted-nearest neighbor (WNN) analysis in Seurat v4 learns per-cell modality weights to define cell states, enabling a 228-antibody human PBMC CITE-seq reference for RNA-only query mapping.