Diet-responsive Transcriptional Regulation of Insulin in a Single Neuron Controls Systemic Metabolism
Ava Handley, Qiuli Wu, Tessa Sherry, Rebecca Cornell, Roger Pocock
The paper shows that ETS-5 in C. elegans BAG neurons regulates INS-1 expression, linking neuronal activity to systemic metabolism through diet-induced changes.
PLoS Biology · May 20, 2022Peer-reviewedGenetics