Author

Heng Kang Hu

Northeast Forestry UniversityORCID 0000-0002-9505-4049Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:long-read sequencing· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Approach:experimental assay· 1 Research Focus:genome assembly· 1 Organism:human· 1 Organism:plant (other)· 1 Research Focus:polygenic risk· 1

Frequent Co-Authors

Guohua WangiD· 2 shared Murong ZhouiD· 2 shared Runtian GaoiD· 2 shared Wentao GaoiD· 2 shared Zhongjun Jiang· 2 shared Shengming ZhouiD· 1 shared Shuilin JiniD· 1 shared Shuqi CaoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioinformatics

Guohua WangORCID

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2 papers

Recent·Most cited

SVPG: A pangenome-based structural variant detection approach and rapid augmentation of pangenome graphs with new samples

Tao Jiang, Heng Kang Hu, Runtian Gao, Shuqi Cao, Zhongjun Jiang, Murong Zhou, Wentao Gao, Shengming Zhou, Guohua Wang

SVPG improves structural variant detection using pangenome references and accelerates pangenome graph construction from long-read data.

Nature Methods · Sep 21, 2026Peer-reviewedBioinformatics

Reference-guided genome assembly at scale using ultra-low-coverage high-fidelity long-reads with HiFiCCL

Zhongjun Jiang, Weihua Pan, Runtian Gao, Heng Kang Hu, Wentao Gao, Murong Zhou, Yu-Hang Yin, Zhipeng Qian, Shuilin Jin, Guohua Wang

HiFiCCL improves ultra-low-coverage genome assembly using high-fidelity long-reads, enhancing structural variant detection and pangenome construction in human and plant datasets.

bioRxiv · Apr 20, 2025 · PreprintBioinformatics