CTDP: Identifying cell types associated with disease phenotypes using scRNA-seq data
Chonghui Liu, Murong Zhou, Zhidong Wang, Yang Chen, Yan Zhang, Zhongjun Jiang, Yu-Hang Yin, Zeyu Luo, Tianjiao Zhang, Guohua Wang, Lei Yuan
CTDP identifies disease-associated cell types using scRNA-seq by integrating Lasso-regularized logistic regression and permutation testing, outperforming existing methods in accuracy and robustness.
bioRxiv · Oct 16, 2025 · PreprintBioinformatics