Sean G. Lacoursiere

This study shows that hippocampal damage in rats impairs visual object memory but preserves odour-based memory in a discrimination task.

This paper describes the generation of a hybrid Alzheimer disease mouse model and shows it reduces cognitive and neuronal deficits compared to APP knock-in mice.

This study shows that gradual cerebral hypoperfusion in AD mouse models causes cortical network dysfunctions and microgliosis, with distinct effects in wild-type and AD mice.

This study shows that gradual cerebral hypoperfusion in mice impairs learning and memory, with evidence of cholinergic dysfunction and neurodegeneration.