GATA2 regulates mast cell identity and responsiveness to antigenic stimulation by promoting chromatin remodeling at super-enhancers
Yapeng Li, Jun‐Feng Gao, Mohammad Zahid Kamran, Laura D. Harmacek, Thomas Danhorn, Sonia M. Leach, Brian P. O’Connor, James R. Hagman, Hua Huang
This study shows GATA2 regulates mast cell identity and antigen responsiveness by enhancing chromatin accessibility at super-enhancers.
Nature Communications · Jan 21, 2021Peer-reviewedMolecular Biology