Shay Stern

Behavioral age-detection in individuals reconstructs minute-scale developmental transcriptomics

The paper introduces BehaveSeq, a method that reconstructs minute-scale developmental transcriptomics by integrating behavioral monitoring with single-cell transcriptomic profiling in C. elegans.

Consolidation of behavioral synchronization with the developmental clock is impaired by the degeneration of a mechanosensory circuit in C. elegans

This study shows that degeneration of a mechanosensory circuit in C. elegans impairs developmental synchronization of behavior, which can be restored by neuroprotection.

Mapping the developmental structure of stereotyped and individual-unique behavioral spaces in C. elegans

The paper creates a developmental atlas of C. elegans behavior by analyzing continuous posture data, revealing both stereotyped and individual-specific behavioral patterns.

Early-life experience reorganizes neuromodulatory regulation of stage-specific behavioral responses and individuality types during development

The paper shows early-life starvation affects behavioral responses at different developmental stages in C. elegans, with dopamine and serotonin having opposite roles, and identifies individuality types shaped by experience.