Author
University of PennsylvaniaORCID 0000-0002-9617-4624Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Nathan H. Lazar, Safiye Çelik, Lu Chen…·Imran S. Haque
The paper identifies a proximity bias in CRISPR-Cas9 knockouts, showing phenotypic similarity between unrelated genes on the same chromosome arm, and proposes a correction method.
Katerina A.B. Gawronski, William P. Bone, YoSon Park…·Christopher D. Brown
The paper identifies cell-type specific splicing quantitative trait loci (sQTLs) in iPSCs and HLCs and shows they contribute to lipid level variation beyond what is captured by gene expression alone.
Brian Y Chen, William P. Bone, Kim Lorenz…·Benjamin F. Voight
ColocQuiaL performs colocalization analysis between GWAS and eQTL/sQTL data to identify candidate causal genes for GWAS signals.
Tiffany R. Bellomo, William P. Bone, Brian Y. Chen…·Scott M. Damrauer
This study performs multi-trait GWAS on atherosclerosis-related traits to identify novel pleiotropic loci and their potential biological mechanisms.
William P. Bone, Katherine M. Siewert, Anupama Jha…·Benjamin F. Voight
This study identifies pleiotropic genetic loci shared between Alzheimer's disease and cardiometabolic traits using bivariate GWAS and colocalization analysis.