BioinformaticseLifePeer-reviewed
Discovering fragment length signatures of circulating tumor DNA using Non-negative Matrix Factorization
Gabriel Renaud, Maibritt Nørgaard, Johan Lindberg…·Søren Besenbacher
This paper uses non-negative matrix factorization to analyze cfDNA fragment length distributions, showing it can infer tumor load, detect cancer, and identify open chromatin-associated signatures.
22 citations