Systems BiologyScientific ReportsPeer-reviewed
BAX and SMAC Regulate Bistable Properties of the Apoptotic Caspase System
Stephanie McKenna, Lucia García-Gutiérrez, David Matallanas, Dirk Fey
This study presents a mathematical model of how BAX and SMAC regulate the bistable properties of the apoptotic caspase system, validated by experimental and computational evidence.
33 citations