Author

Alex Dickson

Michigan State UniversityORCID 0000-0002-9640-1380Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Asmaa Aly· 1 shared Augen A. PioszakiD· 1 shared Benjamin J. OrlandoiD· 1 shared Ceren KılınçiD· 1 shared Katie M. BabiniD· 1 shared Samik BoseiD· 1 shared Seref Berk Atik· 1 shared Vardan T. KaramyaniD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

8 top collaborators · 9 mutual co-author links

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1 shared paperBiophysics

Asmaa Aly

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Assessing the Stability of Molecular Glues with Weighted Ensemble Simulations

Seref Berk Atik, Alex Dickson

This study uses weighted ensemble simulations to assess how molecular glues stabilize protein-protein interactions, showing distinct behaviors that correlate with reported EC50 values.

Journal of Chemical Theory and Computation · Jul 21, 2026Peer-reviewedBiophysics

Determinants of Improved CGRP Peptide Binding Kinetics Revealed by Enhanced Molecular Simulations

Ceren Kılınç, Katie M. Babin, Augen A. Pioszak, Alex Dickson

This study identifies molecular determinants of improved CGRP peptide binding kinetics using enhanced simulations of the CLR:RAMP1 complex and its engineered variant ssCGRP.

Biophysical Journal · Mar 9, 2026Peer-reviewedMolecular Biology

Conformation Driven Enhancement of Neurolysin Activity in Presence of a Small Molecule Activator

Samik Bose, Asmaa Aly, Vardan T. Karamyan, Benjamin J. Orlando, Alex Dickson

This study identifies three binding sites of a small molecule activator on Neurolysin using MD simulations and Markov state modeling, revealing how these sites modulate conformational dynamics and catalytic activity.

bioRxiv · Jan 6, 2026 · PreprintBiophysics