Stephen G. Matthews

Conserved DNA Methylation Signatures in The Prefrontal Cortex of Newborn and Juvenile Guinea Pigs Following Antenatal Corticosteroid Exposure

This study identifies altered DNA methylation patterns in the prefrontal cortex of guinea pig offspring exposed to antenatal corticosteroids at newborn and juvenile ages, with persistent changes at key transcription factor binding sites.

Maternal malnutrition impacts placental morphology and transport. An origin for poor offspring growth and vulnerability to disease.

This study examines how maternal malnutrition affects placental morphology and transport systems in mice, revealing differences in placental development and function between undernourished and high-fat diet groups.