Organotin(IV) Dithiocarbamate Compounds Targeting A549 Lung Cancer Cells via Mitochondria-Mediated Apoptosis
Nurul Amalina Abd Aziz, Normah Awang, Nurul Farahana Kamaludin, Asmah Hamid, Nur Najmi Mohamad Anuar, Kok Meng Chan, Nurul Zahidah Zainirizal
This paper synthesizes and evaluates four organotin(IV) dithiocarbamates, finding DioSn-2 induces apoptosis in A549 cells via mitochondrial damage and oxidative stress.
bioRxiv · Mar 27, 2026 · PreprintCell Biology