Targeting primary and metastatic ovarian cancer with a peptide derived from the human NAF-1/CISD2 protein
Ehud Neumann, Yang Sung Sohn, Ola Karmi, Merav Darash‐Yahana, Alfredo E. Cárdenas, Eli Pikarsky, Ron Elber, Assaf Friedler, Jose' N. Onuchic, Ron Mittler, Rachel Nechushtai
This paper demonstrates that a peptide derived from CISD2/NAF-1 selectively targets and destroys ovarian cancer mitochondria, reducing tumor size and growth in vivo.
Biomedicine & Pharmacotherapy · Jun 8, 2026Peer-reviewedCancer Biology