Imputation of ancient canid genomes reveals inbreeding history over the past 10,000 years
Katia Bougiouri, Sabhrina Gita Aninta, Sophy Charlton, Alex C. Harris, Martin Petr, Alberto Carmagnini, Giedrė Piličiauskienė, Tatiana R. Feuerborn, Lachie Scarsbrook, Kristina A. Tabbada, Povilas Blaževičius, Heidi G. Parker, Shyam Gopalakrishnan, Greger Larson, Elaine A. Ostrander, , Fernando Racimo
This study imputes ancient dog and wolf genomes to analyze inbreeding history over 10,000 years, finding lower inbreeding in ancient populations and associations between low ROH regions and olfaction/immune genes.
Proceedings of the National Academy of Sciences · Nov 24, 2025Peer-reviewedEvolutionary Biology