Alex C. Harris

This study imputes ancient dog and wolf genomes to analyze inbreeding history over 10,000 years, finding lower inbreeding in ancient populations and associations between low ROH regions and olfaction/immune genes.

This study uses a genotype-first approach to identify new mutations related to craniofacial morphology and stature in dogs, highlighting the role of allelic heterogeneity in breed trait selection.

The paper evaluates low-pass whole genome sequencing and imputation in dogs, optimizing variant filtering to reduce imputation error and provides guidelines for GWAS using imputed genotypes.

The paper identifies germline regulatory variants associated with histiocytic sarcoma in flat-coated retrievers using a multi-omics approach and GWAS.