Keir X. X. Yong

This study simulates visual deficits in healthy adults to determine if incomplete letter recognition issues in dementia patients are due to cortical or optical factors, finding cortical factors are more significant.

This study identifies graded multidimensional variations in cognition and brain volumes between Alzheimer's disease and posterior cortical atrophy, suggesting shared phenotypic continua rather than distinct categories.

This paper introduces SuStaIn, a machine learning method that identifies disease subtypes and their temporal progression from cross-sectional data, improving prediction of diagnostic conversion in neurodegenerative diseases.

This paper introduces KDEMM for disease progression modeling, showing it outperforms GMMs in simulating cognitive data and aligns better with clinical phenotypes in Alzheimer's subtypes.