Yingqiang Shen

BoYueGRN: Zero-shot causal discovery of directed gene regulatory networks from single-cell transcriptomes via amortized inference over synthetic structural causal models

BoYueGRN infers directed gene regulatory networks from single-cell transcriptomes using synthetic structural causal models, achieving high directional accuracy on CRISPRi screens and disease-specific GRN dynamics.

PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP

This study identifies PA28γ's role in promoting oral squamous cell carcinoma progression by enhancing mitochondrial function through interaction with C1QBP.