Qianming Chen

The paper introduces three physics-inspired computational methods for spatial transcriptomics to analyze oral mucosal carcinogenesis, identifying a dysplasia-restricted MRB cluster with autocrine signaling and a density-asymmetric niche.

This study identifies PA28γ's role in promoting oral squamous cell carcinoma progression by enhancing mitochondrial function through interaction with C1QBP.

This study uses single-cell RNA sequencing and immune repertoire analysis to identify key immune cell subtypes and molecular changes in pemphigus vulgaris and assess the impact of prednisone treatment.

SELINA improves cell type annotation in single-cell RNA-seq by addressing batch effects and rare cell type characterization using domain adaptation and synthetic oversampling.