Author

Samiha S. Shaikh

University of CambridgeORCID 0000-0002-9757-6529Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Geoff WoodsiD· 2 shared Ichrak DrissiiD· 2 shared Achim KlessiD· 1 shared Aidan P. NickersoniD· 1 shared Emanuele SheriD· 1 shared Fiona S. Cusdin· 1 shared John E. LinleyiD· 1 shared Mike Nahorski· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersGenetics

Geoff WoodsORCID

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2 papers

Recent·Most cited

A pain-reducing Kv6.4 variant spares other Kv6 channels, offering a target for uterine pain

Ichrak Drissi, Wen Hui Ng, Samiha S. Shaikh, Aidan P. Nickerson, Emanuele Sher, Achim Kless, Geoff Woods

The paper identifies a Kv6.4 variant that selectively reduces function without affecting other Kv6 subunits, suggesting it as a therapeutic target for uterine pain.

bioRxiv · Dec 21, 2025 · PreprintGenetics

Painless Nav1.7 mutations reveal function-critical residuesin the outer vestibule and N-terminus

Nivedita Sarveswaran, Ichrak Drissi, Samiha S. Shaikh, Mike Nahorski, Fiona S. Cusdin, John E. Linley, Geoff Woods

The paper functionally characterizes six SCN9A missense variants associated with CIP, revealing that they cause complete loss-of-function through structural changes in the extracellular vestibule, ion selectivity filter, and N-terminus.

bioRxiv · May 12, 2025 · PreprintMolecular Biology