Author

Achim Kless

Eli Lilly (United Kingdom)ORCID 0000-0001-8301-5934Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Aidan P. NickersoniD· 2 shared Anthony Edward PickeringiD· 1 shared Corin Charman· 1 shared Emanuele SheriD· 1 shared Geoff WoodsiD· 1 shared Graeme W. T. NewtoniD· 1 shared Ichrak DrissiiD· 1 shared James DunhamiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersGenetics

Aidan P. NickersonORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintDec 21, 2025

A pain-reducing Kv6.4 variant spares other Kv6 channels, offering a target for uterine pain

Ichrak Drissi, Wen Hui Ng, Samiha S. Shaikh…·Geoff Woods

The paper identifies a Kv6.4 variant that selectively reduces function without affecting other Kv6 subunits, suggesting it as a therapeutic target for uterine pain.

DOI 10.64898/2025.12.18.692915

humanbulk RNA-seq

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Genetic & Genomic MedicinemedRxivPreprintMar 12, 2025

Carriers of SCN9A variants linked to inherited and acquired pain syndromes show no alteration in the prevalence of pain or analgesic usage in the UK Biobank cohort

Graeme W. T. Newton, Corin Charman, Aidan P. Nickerson…·Anthony Edward Pickering

2 citations

humanwhole-exome sequencing

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GeneticsPainPeer-reviewedDec 17, 2021

Genome-wide association study of pain sensitivity assessed by questionnaire and the cold pressor test

Pierre Fontanillas, Achim Kless, John Bothmer, Joyce Y. Tung

This study conducts GWAS on pain sensitivity measured by questionnaire and cold pressor test, identifying one significant locus and genetic correlations with pain conditions and risk factors.

23 citations

humanGWAS summary statistics

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