Reprogrammed Human Lateral Ganglionic Eminence Precursors Generate Striatal Neurons and Restore Motor Function in a Rat Model of Huntington's Disease.
Amy McCaughey‐Chapman, Anne Lieke Burgers, Catharina Combrinck, Laura Marriott, David Gordon, Bronwen J. Connor
This paper demonstrates that human lateral ganglionic eminence precursors generated from fibroblasts can survive transplantation and restore motor function in a rat model of Huntington's disease.
Stem Cell Research & Therapy · Nov 22, 2024Peer-reviewedNeuroscience