Author

Tianyu Zhang

Carnegie Mellon UniversityORCID 0000-0002-9786-7246Unclaimed ORCID profile · follow to get notified of new preprints

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Tianyu Zhang4 papers · China Agricultural University

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Assay:GWAS summary statistics· 1 Approach:machine learning (classical)· 1 Research Focus:polygenic risk· 1

Frequent Co-Authors

Kathryn RoederiD· 2 shared Alexandra ChouldechovaiD· 1 shared Bernie DevliniD· 1 shared Ergan ShangiD· 1 shared Geyu ZhouiD· 1 shared Hongyu ZhaoiD· 1 shared Lambertus KleiiD· 1 shared Max G’Sell· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 29 mutual co-author links

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2 shared papersGenomics

Kathryn RoederORCID

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2 papers

Recent·Most cited

Genetic Convergence Analysis of CRISPR Perturbations Deciphers Gene Functional Similarity

Tianyu Zhang, Ergan Shang, Kathryn Roeder

The paper introduces XConTest, a method to assess genetic convergence in CRISPR perturbations, showing it identifies genes with similar downstream effects in autism and immune response studies.

bioRxiv · Nov 13, 2025 · PreprintGenomics

Evaluating and Improving Health Equity and Fairness of Polygenic Scores

Tianyu Zhang, Geyu Zhou, Lambertus Klei, Peng Liu, Alexandra Chouldechova, Hongyu Zhao, Kathryn Roeder, Max G’Sell, Bernie Devlin

This paper improves the portability and fairness of polygenic scores by introducing Joint-Lassosum, which outperforms existing methods in diverse ancestries.

Human Genetics and Genomics Advances · Feb 23, 2024Peer-reviewedGenetics