Author

Ana Maria Murta Santi

InsermORCID 0000-0002-9791-6554Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Gerald Frank SpaethiD· 3 shared Juliana Pipoli da FonsecaiD· 3 shared Thomas CokelaeriD· 3 shared Aïda BouratbineiD· 1 shared Andrey L. KaramysheviD· 1 shared Blaise LiiD· 1 shared Cristian Camilo Rodríguez-AlmonacidiD· 1 shared Delphine Bacq‐Daian· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersGenomics

Gerald Frank SpaethORCID

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3 papers

Recent·Most cited

Initiation codon context governs translation-coupled mRNA decay and coordinated expression in the human parasite Leishmania

Ana Maria Murta Santi, Thomas Cokelaer, Juliana Pipoli da Fonseca, Paul JENKINS, Elena B. Tikhonova, Cristian Camilo Rodríguez-Almonacid, Andrey L. Karamyshev, Zemfira N. Karamysheva, Gerald Frank Spaeth

This study shows that the Kozak sequence context influences mRNA stability and protein expression in Leishmania by modulating translation-coupled decay and polysome recruitment.

bioRxiv · Oct 6, 2026 · PreprintGenomics

KozakExplorer: an interactive framework for genome-wide Kozak sequence analysis

Thomas Cokelaer, Ana Maria Murta Santi, Juliana Pipoli da Fonseca, Gerald Frank Späth

KozakExplorer quantitatively analyzes translation initiation signals across genomes, revealing evolutionary patterns in eukaryotes and prokaryotes.

bioRxiv · Jun 26, 2026 · PreprintBioinformatics

Genetic introgression and transcriptomic plasticity are associated with enhanced Leishmania infantum pathogenicity causing human cutaneous leishmaniasis in Tunisia

Ana Maria Murta Santi, Blaise Li, Laura Piel, Juliana Pipoli da Fonseca, Delphine Bacq‐Daian, Robert Olaso, Jean‐François Deleuze, Thomas Cokelaer, Karim Aoun, Aïda Bouratbine, Gerald Frank Späth

The paper identifies hybridization between Leishmania species as a driver of pathogenicity shift in Leishmania infantum causing cutaneous leishmaniasis.

bioRxiv · Jun 22, 2026 · PreprintGenomics