Laura Piel

The paper uses a five-layer systems analysis to show that protein degradation, not genomic changes, drives stage differentiation in Leishmania parasites.

The paper identifies hybridization between Leishmania species as a driver of pathogenicity shift in Leishmania infantum causing cutaneous leishmaniasis.

This study uses scRNA-seq to identify gene expression profiles of asexual and sexual merozoites in Plasmodium falciparum, revealing key genes involved in invasion and sexual commitment.

The paper shows genome instability in Leishmania enables fitness gain through epistatic gene copy number variations and compensatory post-transcriptional mechanisms.