Free fatty acids increase basal glucose uptake by adipocytes leveling it to insulin stimulated uptake
Nikita V. Podkuychenko, Polina A. Bogdanova, Veronika S. Perelygina, Andrey N. Tikhonov, Gennadii A. Badun, Maria V. Sudnitsyna, Alexander V. Vorotnikov
This study shows that free fatty acids increase basal glucose uptake in adipocytes through GLUT4 translocation, but do not affect insulin-stimulated uptake, suggesting a context-dependent role in insulin resistance.
bioRxiv · Dec 13, 2025 · PreprintMolecular Biology