Author

Guiyun Zhao

Zhejiang UniversityORCID 0000-0002-9795-4235Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Jingkun ShiiD· 2 shared Miaolian WuiD· 2 shared Yi‐Ling DuiD· 2 shared Binju WangiD· 1 shared Feng YuiD· 1 shared Hu LiiD· 1 shared Huisi HuangiD· 1 shared Jian She Yang· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

Jingkun ShiORCID

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2 papers

Recent·Most cited

Structural and mechanistic insights into bacterial hydrazine biosynthesis

Guiyun Zhao, Huisi Huang, Yifan Li, Jianli Yang, Yuan‐Yang Guo, Liqiao Xu, Lu Wang, Jingkun Shi, Miaolian Wu, Feng Yu, Binju Wang, Zhimin Zhang, Yi‐Ling Du

This study determines the crystal structures of bacterial hydrazine synthetases and elucidates their mechanism, enabling the expansion of hydrazine biosynthesis through novel enzyme discovery and chemoenzymatic synthesis.

Journal of the American Chemical Society · Nov 5, 2025Peer-reviewedMicrobiology

Genome Mining and Characterization of a Heme-Dependent Enzyme Catalyzing Intermolecular Nitrogen-Nitrogen Bond Formation in Hydrazinosuccinic Acid Biosynthesis

Jingkun Shi, Zhijie Zhao, Jian She Yang, Ziyang Cheng, Hu Li, Yu Liu, Guiyun Zhao, Miaolian Wu, Yi‐Ling Du

The paper discovers and characterizes a heme-dependent enzyme system that catalyzes intermolecular N-N bond formation using inorganic nitrogen sources.

Synthetic and Systems Biotechnology · Aug 18, 2025Peer-reviewedBiochemistry