Laura Baumgartner

Parallel Networks to simulate complex multicellular dynamics - A proof of concept with intervertebral disc cell systems

The paper introduces a mathematical methodology to simulate multicellular system dynamics under multifactorial stimuli using parallel networks.

Parallel networks to predict TIMP and protease cell activity of Nucleus Pulposus cells exposed and not exposed to pro-inflammatory cytokines

The paper uses a Parallel Network methodology to predict TIMP and protease activity in NP cells under various mechanical and inflammatory conditions.

Simulating intervertebral disc cell behavior within 3D multifactorial environments

This paper develops a hybrid Agent-based model to simulate intervertebral disc cell behavior in 3D multifactorial environments, showing cell death and viability changes under simulated stress conditions.