Author

Nicholas J. Porter

California Institute of TechnologyORCID 0000-0002-9803-5310Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1

Frequent Co-Authors

Ella J. Watkins‐DulaneyiD· 1 shared Frances H. ArnoldiD· 1 shared Grace LiuiD· 1 shared Jason YangiD· 1 shared Kadina E. JohnstoniD· 1 shared Patrick J. AlmhjelliD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBioengineering

Ella J. Watkins‐DulaneyORCID

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1 paper

Recent·Most cited

BioengineeringProceedings of the National Academy of SciencesPeer-reviewedJul 29, 2024

A combinatorially complete epistatic fitness landscape in an enzyme active site

Kadina E. Johnston, Patrick J. Almhjell, Ella J. Watkins‐Dulaney…·Frances H. Arnold

The paper constructs a large-scale sequence-fitness dataset for enzyme engineering, revealing significant epistasis and highlighting challenges in predicting optimal variants.

56 citationstop 2%

protein sequenceexperimental assay

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