Siyuan Huang

Benchmarking algorithms for spatially variable gene identification in spatial transcriptomics

This paper benchmarks algorithms for identifying spatially variable genes in spatial transcriptomics using synthesized and real-world datasets to evaluate their effectiveness and application scenarios.

Radiation damage behavior of soft matter in ultrafast cryo-electron microscopy (cryo-UEM)

This study investigates whether pulsed-electron imaging in ultrafast cryo-EM mitigates radiation damage, finding no significant mitigation effect despite varying experimental conditions.

Directly selecting differentially expressed genes for single-cell clustering analyses

This paper introduces Festem, a method that directly selects differentially expressed genes for single-cell clustering, improving cell-type identification and reducing selection bias.

A Novel Gene ZNF862 Causes Hereditary Gingival Fibromatosis

The paper identifies a novel heterozygous missense mutation in ZNF862 as the cause of autosomal-dominant non-syndromic hereditary gingival fibromatosis in a Chinese family.