Anoop Manjunath

This study uses single-cell RNA-sequencing to analyze cell type-specific responses to young or aged blood in heterochronic parabiosis, identifying mitochondrial function as a key factor in rejuvenation.

The paper introduces CytoTRACE, a method using transcriptional diversity to predict differentiation states from scRNA-seq data, outperforming existing methods and identifying stem cells and tumor-related genes.

The paper creates a single-cell transcriptomic atlas of 20 mouse organs and tissues, providing a resource for studying gene expression across cell types.