The paper identifies three cryptic lineages of Aedes notoscriptus mosquitoes using population genomics, revealing reproductive isolation and structural variants between lineages.

bioRxiv · Sep 14, 2026 · PreprintEvolutionary Biology

Populations of the Australian saltmarsh mosquito Aedes vigilax vary between panmixia and temporally stable local genetic structure

Thomas L. Schmidt, Nancy M. Endersby‐Harshman, Toby J. T. Mills, Rahul Rane, Gunjan Pandey, Christopher M. Hardy, Leon N. Court, Cameron Ewart Webb, Brendan J. Trewin, Brett Anthony Neilan, Ary A. Hoffmann

This study uses genomic data to show that Aedes vigilax mosquito populations exhibit varying genetic structures between panmixia and localized stability, with implications for pest management.

Evolutionary Applications · Jun 1, 2025Peer-reviewedEvolutionary Biology

Global, asynchronous partial sweeps at multiple insecticide resistance genes in Aedes mosquitoes

Thomas L. Schmidt, Nancy M. Endersby‐Harshman, Anthony R. J. van Rooyen, Michelle Katusele, Rebecca Vinit, Leanne J. Robinson, Moses Laman, Stephan Karl, Ary A. Hoffmann

The paper identifies partial selective sweeps at insecticide resistance genes in Aedes mosquitoes, showing independent evolution and spread of resistance alleles across different regions.

Nature Communications · Jul 24, 2024Peer-reviewedEvolutionary Biology

Genomic databanks and targeted assays help characterise domestic mosquito incursions

Thomas L. Schmidt, Nancy M. Endersby‐Harshman, Nina Kurucz, William Pettit, Vicki Krause, Gerhard JM Ehlers, Mutizwa Odwell Muzari, Bart J. Currie, Ary A. Hoffmann

The paper uses genomic databanks and targeted assays to trace mosquito incursions and shows genomic tracing remains effective despite genetic divergence.

bioRxiv · Jan 19, 2022 · PreprintGenomics

Voltage-sensitive sodium channel (Vssc) mutations associated with pyrethroid insecticide resistance in Aedes aegypti (L.) from Jeddah, Kingdom of Saudi Arabia - baseline information for a Wolbachia release program

Nancy M. Endersby‐Harshman, AboElgasim Ali, Basim Alhumrani, Mohammed Alkuriji, Mohammed B. Al-Fageeh, Abdulaziz Almalik, Mohammed S. Alsuabeyl, Samia Elfékih, Ary A. Hoffmann

This study identifies Vssc mutations associated with pyrethroid resistance in Ae. aegypti from Jeddah, providing baseline data for a Wolbachia release program.

Parasites & Vectors · Jul 11, 2021Peer-reviewedGenetics

A LAMP assay for the rapid and robust assessment of Wolbachia infection in Aedes aegypti under field and laboratory conditions

Moshe E. Jasper, Qiong Yang, Perran A. Ross, Nancy M. Endersby‐Harshman, Nicholas Bell, Ary A. Hoffmann

The paper validates a modified LAMP assay for rapid, sensitive, and specific detection of wAlbB Wolbachia infection in Aedes aegypti under field and lab conditions.

PLoS ONE · Nov 20, 2019Peer-reviewedGenetics

Tracking genetic invasions: genome-wide SNPs reveal the source of pyrethroid-resistant Aedes aegypti (yellow fever mosquito) incursions at international ports

Thomas L. Schmidt, Anthony R. J. van Rooyen, Jessica Chung, Nancy M. Endersby‐Harshman, Philippa C. Griffin, Angus Sly, Ary A. Hoffmann, Andrew Raymond Weeks

The paper uses genome-wide SNPs to trace the origin of pyrethroid-resistant Aedes aegypti incursions at international ports, identifying Bali and Pacific Islands as key sources.

Evolutionary Applications · Mar 6, 2019Peer-reviewedGenomics