A mouse model of ZTTK syndrome reveals indispensable SON functions in organ development and hematopoiesis
Lana Vukadin, Bohye Park, Mostafa Mohamed, Huashi Li, Amr Elkholy, Alex Torrelli-Diljohn, Jung‐Hyun Kim, Kyuho Jeong, James M. Murphy, Caitlin A. Harvey, Sophia Dunlap, Leah Gehrs, Hanna Lee, Hyung‐Gyoon Kim, Seth N. Lee, , Eun-Young Erin Ahn
This study develops a mouse model of ZTTK syndrome by creating Son haploinsufficiency mice, revealing critical roles of SON in organ development and hematopoiesis.
bioRxiv · Nov 19, 2023 · PreprintGenetics