Denise D. Stanford

PDE4 Inhibitor Apremilast Rebalances Inflammatory Responses to Pseudomonas aeruginosa Infection in CF Rats

This study evaluates apremilast's ability to modulate inflammation in CF rats infected with Pseudomonas aeruginosa, showing preserved lung function and reduced injury without increasing bacterial burden.

Pulmonary Fibrosis Ferret Model Demonstrates Sustained Fibrosis, Restrictive Physiology, and Aberrant Repair

This study shows that bleomycin-exposed ferrets develop sustained pulmonary fibrosis, restrictive lung physiology, and airway remodeling similar to human IPF.

A mouse model of ZTTK syndrome reveals indispensable SON functions in organ development and hematopoiesis

This study develops a mouse model of ZTTK syndrome by creating Son haploinsufficiency mice, revealing critical roles of SON in organ development and hematopoiesis.