Author

Ana Hernández-Plaza

Instituto Nacional de Investigación y Tecnología Agraria y AlimentariaORCID 0000-0002-9844-7999Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:database / resource· 2 Research Focus:gene regulatory network inference· 2 Assay:protein sequence· 2 Research Focus:software / tool· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Jaime Huerta‐CepasiD· 3 shared Carlos P. CantalapiedraiD· 2 shared Peer Bork BiD· 2 shared Adrián DavíniD· 1 shared Alexander J. TarashanskyiD· 1 shared Andrea B. KohniD· 1 shared Anna KreshukiD· 1 shared Bo WangiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBioinformatics

Jaime Huerta‐CepasORCID

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3 papers

Recent·Most cited

BioinformaticsMolecular Biology and EvolutionPeer-reviewedJan 30, 2026

TreeProfiler: Large-scale metadata profiling along gene andspecies trees

Ziqi Deng, Claudia Sanchis-López, Ana Hernández-Plaza…·Jaime Huerta‐Cepas

TreeProfiler profiles biological traits along gene and species trees, enabling analysis of functional diversification and species abundance across biomes.

4 citations

bacteria (other)protein sequence

𝕏 PostBluesky

Developmental BiologySciencePeer-reviewedNov 4, 2021

Profiling cellular diversity in sponges informs animal cell type and nervous system evolution

Jacob M. Musser, Klaske J. Schippers, Michael Nickel…·Detlev Arendt

The paper identifies 18 cell types in sponges, including neuroid cells with synaptic gene expression, suggesting early neuro-immune system evolution.

242 citationstop 1%

scRNA-seqstatistical model

𝕏 PostBluesky

BioinformaticsMolecular Biology and EvolutionPeer-reviewedSep 30, 2021

✦ In-depth digest

eggNOG-mapper v2: Functional Annotation, Orthology Assignments, and Domain Prediction at the Metagenomic Scale

Carlos P. Cantalapiedra, Ana Hernández-Plaza, Ivica Letunić…·Jaime Huerta‐Cepas

Rebuilt on eggNOG v5, eggNOG-mapper v2 raises average annotation rate by 608% over v1 and adds Prodigal gene calling, pairwise ortholog reports, and PFAM/SMART domain prediction.

5,338 citationstop 1%

multiple speciesmetagenomics

𝕏 PostBluesky