Detlev Arendt

This study shows that cholinergic and monoaminergic signaling originated before Bilateria, using a combination of metabolomics, phylogenetics, and single-cell analysis.

This paper introduces a mobile optical coherence microscope for high-resolution, label-free imaging of aquatic organisms in both lab and field settings, enabling detailed morphological and dynamic analysis.

The paper maps a whole-body single-cell transcriptome into an electron microscopy volume of an annelid worm to study cellular morphology and gene regulation.

The paper compares gene expression in convergent jellyfish eyes, finding mostly lineage-specific expression but shared conserved vision genes across species.

Spotiflow improves spot detection in microscopy images using deep learning, achieving subpixel accuracy and efficiency across diverse datasets.

This study uses single-cell and spatial transcriptomics to analyze shark telencephalon development, revealing ancient origins of basal progenitors and Cajal-Retzius cells in gnathostomes.

The paper presents genome assemblies for three Platynereis species to support comparative genomic studies and explore their biology.

This study challenges the ortholog conjecture by analyzing scRNA-seq data across species, revealing gene-specific patterns of expression conservation and divergence.

This study shows that local regeneration in sea anemones triggers a systemic homeostatic response leading to whole-body tissue remodeling through proteolysis driven by metalloproteases.

The paper shows that vertebral segmentation during axolotl tail regeneration occurs via a buckling instability mechanism, distinct from the somite-based process in embryonic development.

The paper identifies an ancient relaxant-inflammatory response in sponges during deflation, driven by actomyosin relaxation and associated with inflammation-like states.

MoBIE is a Fiji plugin that enables visualization, sharing, and management of large, multi-modal image data across platforms.

The paper introduces an unsupervised method to extract morphological features from 3D EM data, enabling cell type and tissue organization analysis in a segmented worm.

The paper uses scRNA-seq to identify cell types in sea urchin larvae, revealing neuronal and gene regulatory networks with evolutionary implications.

The paper identifies 18 cell types in sponges, including neuroid cells with synaptic gene expression, suggesting early neuro-immune system evolution.

The paper uses SAMap to compare single-cell atlases across species, identifying homologous cell types and revealing ancient cell families in animal evolution.

The paper maps the developmental cell lineage of the annelid brain from zygote to mid-trochophore stage and identifies a subdivision of the larval brain into proliferative and differentiating regions.

The paper studies chemosensory activity in Platynereis dumerilii using microfluidics and calcium imaging, identifying antennae as the primary chemosensory organs and reporting activity in brain regions similar to insect mushroom bodies.

The paper identifies a telencephalon-like region in the adult amphioxus brain with molecular and developmental features similar to vertebrates, suggesting a key link in chordate brain evolution.

The paper uses single-cell sequencing to identify apical and non-apical tissue subdivisions in Platynereis larva.