Human skeletal muscle possesses an epigenetic memory of high intensity interval training
Andrea Pilotto, Daniel C. Turner, Emanuela Crea, Raffaele Mazzolari, Lorenza Brocca, Maria Antonietta Pellegrino, Danilo Miotti, Roberto Bottinelli, Adam Philip Sharples, Simone Porcelli
This study shows that human skeletal muscle retains epigenetic memory of high-intensity interval training (HIIT) through hypomethylation and increased gene expression even after detraining.
American Journal of Physiology-Cell Physiology · Nov 21, 2024Peer-reviewedPhysiology