Author

Simone Porcelli

University of PaviaORCID 0000-0002-9494-0858Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Assay:electronic health records· 1 Assay:electrophysiology· 1 Assay:imaging· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Andrea PilottoiD· 2 shared Adam Philip SharplesiD· 1 shared Alberto BotteriD· 1 shared Andrea Menditto· 1 shared Beth Minion· 1 shared Callum G. BrownsteiniD· 1 shared Chiara Felles· 1 shared Clarissa Müller BruscoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersNeuroscience

Andrea PilottoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Sex differences in durability following heavy intensity cycling exercise in trained athletes

Elisa Pastorio, Pádraig Spillane, Emma Squires, Leila Benyahia, Hannah Kate Wilson, Patrick Swain, Marta Colosio, Chiara Felles, Andrea Menditto, Samuel Clarke, Beth Minion, Will Pearmain, Callum G. Brownstein, Simone Porcelli, Paul Ansdell

This study examines sex differences in durability during heavy intensity cycling, finding males experience greater reductions in key physiological thresholds compared to females.

Scandinavian Journal of Medicine and Science in Sports · Apr 1, 2026Peer-reviewedPhysiology

Motor unit behaviour adaptations across the lifespan: sex differences in young, middle-aged and old adults

Marco Carbonaro, Marta Boccardo, Clarissa Müller Brusco, Andrea Pilotto, Rebecca Re, Fulvio Lauretani, Simone Porcelli, Martino Vladimiro Franchi, Alberto Botter

This study examines age- and sex-related differences in motor unit firing behavior across young, middle-aged, and older adults, revealing sex-specific neuromuscular aging patterns.

bioRxiv · Dec 22, 2025 · PreprintNeuroscience

Human skeletal muscle possesses an epigenetic memory of high intensity interval training

Andrea Pilotto, Daniel C. Turner, Emanuela Crea, Raffaele Mazzolari, Lorenza Brocca, Maria Antonietta Pellegrino, Danilo Miotti, Roberto Bottinelli, Adam Philip Sharples, Simone Porcelli

This study shows that human skeletal muscle retains epigenetic memory of high-intensity interval training (HIIT) through hypomethylation and increased gene expression even after detraining.

American Journal of Physiology-Cell Physiology · Nov 21, 2024Peer-reviewedPhysiology