Author

Siyuan Cheng

Yale UniversityORCID 0000-0002-9910-0241Unclaimed ORCID profile · follow to get notified of new preprints

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Siyuan Cheng3 papers · Southen University of Science and Technology;

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Isaac Yi KimiD· 1 shared Jiaying Qian· 1 shared Ping MuiD· 1 shared Su DengiD· 1 shared Xiao JiniD· 1 shared Yuyin JiangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

Isaac Yi KimORCID

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1 paper

Recent·Most cited

ATHENA: A deep learning-based AI for functional prediction of genomic mutations and synergistic vulnerabilities in prostate cancer

Siyuan Cheng, Xiao Jin, Jiaying Qian, Yuyin Jiang, Isaac Yi Kim, Su Deng, Ping Mu

ATHENA predicts functional genomic mutations and synergistic vulnerabilities in prostate cancer using deep learning, identifying driver events and therapeutic targets through integration with variant discovery pipelines.

bioRxiv · Nov 26, 2025 · PreprintCancer Biology