Author

Saskia M. Brachmann

Novartis (Switzerland)ORCID 0000-0002-9912-0971Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Andreas WeissiD· 1 shared Andrew J. AguirreiD· 1 shared Aparna PadhyeiD· 1 shared Clint A. StalneckeriD· 1 shared Daniela Schildknecht· 1 shared David S. Quinn· 1 shared Eejung KimiD· 1 shared Elena J. OrlandoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioinformatics

Andreas WeissORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 2, 2026

KRASG12C Inhibition Remodels the Non-Small Cell Lung Cancer Surfaceome to Uncover Targetable Vulnerabilities

Aparna Padhye, Kalisa Kang, Fan Yi Kong…·Joseph Douglas Mancias

This study shows that KRASG12C inhibitors alter the surface proteome of lung cancer cells, revealing FOLR1 as a new target when combined with an antibody drug conjugate.

DOI 10.64898/2026.10.01.756013

humanproteomics

𝕏 PostBluesky

BioinformaticsbioRxivPreprintNov 26, 2025

Sample-level modeling of single-cell data at scale with tinydenseR

Pedro Milanez‐Almeida, Daniela Schildknecht, Markus Linder…·Elena J. Orlando

tinydenseR detects differential cell state density across samples in single-cell data, outperforming existing methods in speed and memory usage.

DOI 10.1101/2025.11.26.690752

scRNA-seqstatistical model

𝕏 PostBluesky