Author

Igor Zhukov

Institute of Biochemistry and Biophysics, Polish Academy of SciencesORCID 0000-0002-9912-1018Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1

Frequent Co-Authors

Magdalena J. ŚlusarziD· 2 shared Natalia KarskaiD· 2 shared Sylwia Rodziewicz‐MotowidłoiD· 2 shared Andrea D. LipińskaiD· 1 shared Behnaz Mizraeli· 1 shared Małgorzata GrauliD· 1 shared Przemysław KarpowicziD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

Magdalena J. ŚlusarzORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Membrane-dependent structural organization of cowpox virus CPXV012 and its recognition of TAP

Natalia Karska, Behnaz Mizraeli, Magdalena J. Ślusarz, Przemysław Karpowicz, Igor Zhukov, Sylwia Rodziewicz‐Motowidło

This study investigates the membrane-dependent structure of CPXV012 and its interaction with TAP, revealing a two-helical organization and flexible ER-luminal region critical for TAP recognition.

bioRxiv · Jun 13, 2026 · PreprintBiochemistry

Unlocking viral evasion: Luminal charge interactions in BoHV-1 UL49.5 allosterically control TAP degradation

Natalia Karska, Małgorzata Graul, Igor Zhukov, Sylwia Rodziewicz‐Motowidło, Andrea D. Lipińska, Magdalena J. Ślusarz

This study identifies N-terminal electrostatic interactions in BoHV-1 UL49.5 as allosteric determinants of TAP degradation, showing that TAP degradation can be uncoupled from MHC class I downregulation.

bioRxiv · Jun 12, 2026 · PreprintBiochemistry