Author

Yi Kai Zhou

University of California, Los AngelesORCID 0000-0002-9912-581XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Arjun GuttaiD· 1 shared Candace ChangiD· 1 shared Diana A. Chernikova· 1 shared Fengting LiangiD· 1 shared Jamilla Situ· 1 shared Jonathan P. JacobsiD· 1 shared Julianne Ching YangiD· 1 shared Matthew Y. ZhaoiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Arjun GuttaORCID

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1 paper

Recent·Most cited

The ZIP8 A391T Crohn's disease-linked risk variant induces colonic metal ion dyshomeostasis, microbiome compositional shifts, and inflammation

Julianne Ching Yang, Matthew Y. Zhao, Diana A. Chernikova, Nerea Arias-Jayo, Yi Kai Zhou, Jamilla Situ, Arjun Gutta, Candace Chang, Fengting Liang, Venu Lagishetty, Jonathan P. Jacobs

This study shows that the SLC39A8 A391T variant reduces luminal trace metals and alters microbiome composition in mice, leading to spontaneous colonic inflammation.

Digestive Diseases and Sciences · Sep 25, 2024Peer-reviewedGenomics