Author

Yiyang Lu

University of Illinois Urbana-ChampaignORCID 0000-0002-9913-0416Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Approach:variational autoencoder· 1

Frequent Co-Authors

Diwakar ShuklaiD· 1 shared Jesse R. Horne· 1 shared Roy D. DariD· 1 shared Shivank NagiD· 1 shared Sohom Dash· 1 shared Xuenan MiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

Diwakar ShuklaORCID

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1 paper

Recent·Most cited

Variational Autoencoder-enabled High-throughput Drug Screening for HIV Latency Modulators predicted through Noise in Gene Expression

Yiyang Lu, Jesse R. Horne, Xuenan Mi, Shivank Nag, Sohom Dash, Roy D. Dar, Diwakar Shukla

This study uses a variational autoencoder to screen ~175,000 compounds for HIV latency modulators, identifying 16 LRAs and 2 LPAs with a 15.9% experimental hit rate.

bioRxiv · Jul 9, 2026 · PreprintBiochemistry