BiochemistrybioRxivPreprint
Variational Autoencoder-enabled High-throughput Drug Screening for HIV Latency Modulators predicted through Noise in Gene Expression
Yiyang Lu, Jesse R. Horne, Xuenan Mi…·Diwakar Shukla
This study uses a variational autoencoder to screen ~175,000 compounds for HIV latency modulators, identifying 16 LRAs and 2 LPAs with a 15.9% experimental hit rate.
DOI 10.64898/2026.07.08.737074