Author

Christopher J. Lingle

Washington University in St. LouisORCID 0000-0002-9916-3795Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Assay:electrophysiology· 2 Approach:experimental assay· 2

Frequent Co-Authors

Xiao-Ming XiaiD· 2 shared Yu ZhouiD· 2 shared Gopal S. KallureiD· 1 shared Sandipan Roy ChowdhuryiD· 1 shared Vivian M. Gonzalez-PereziD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersBiophysics

Xiao-Ming XiaORCID

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2 papers

Recent·Most cited

β2 and β3a regulatory subunits can coassemble in the same BK channels

Yu Zhou, Vivian M. Gonzalez-Perez, Xiao-Ming Xia, Gopal S. Kallure, Sandipan Roy Chowdhury, Christopher J. Lingle

The paper investigates whether β2 and β3a BK channel regulatory subunits can coassemble in the same channel complex and finds they do so randomly.

The Journal of General Physiology · Nov 25, 2025Peer-reviewedBiophysics

Disruption of a side portal pathway permits closed-state inactivation by BK β subunit N-termini

Yu Zhou, Xiao-Ming Xia, Christopher J. Lingle

The paper investigates how mutations in BK channel β subunit residues affect inactivation by altering access to the central cavity through the side portal pathway.

The Journal of General Physiology · Apr 29, 2025Peer-reviewedBiophysics